Plasmid shRNAs

We offer a comprehensive catalog of over 27,000 shRNA plasmid sets targeting the human genome. For most customers, we recommend performing initial testing with shRNAs in a viral vector backbone (i.e., transfect with the shRNA plasmids and validate in vitro). We guarantee at least 70% knockdown of your gene of interest with our designed shRNA vectors. Once you have determined the best shRNA for your experiments, we can then package your validated AAV vector for efficient gene knockdown in vivo.